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目的研究无创通气对慢性阻塞性肺疾病急性加重期(AECOPD)并肺性脑病患者的临床疗效。方法回顾性分析2008年6月至2012年6月在粤北人民医院呼吸内科行无创通气的AECOPD并肺性脑病的78例患者的临床资料,监测通气前及通气后2、12及24 h后的血气分析变化,观察患者的治疗转归及无创正压通气治疗的不良反应。结果与通气前比较,通气后患者临床症状逐渐改善,动脉血二氧化碳分压水平降低(P<0.01),动脉血氧分压水平升高(P<0.01),pH值升高(P<0.01)。结论无创通气对AECOPD并肺性脑病的患者有良好的治疗效果,值得临床推广。
Objective To study the clinical efficacy of non-invasive ventilation in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and pulmonary encephalopathy. Methods The clinical data of 78 patients with non-invasive AECOPD and pulmonary encephalopathy in Department of Respiratory Medicine of Yuebei People’s Hospital from June 2008 to June 2012 were retrospectively analyzed. Before and after ventilation, 2,12 and 24 h Analysis of changes in blood gas to observe the outcome of treatment and non-invasive treatment of positive pressure ventilation adverse reactions. Results Compared with those before ventilation, the symptoms of patients gradually improved, the arterial carbon dioxide partial pressure decreased (P <0.01), the arterial partial pressure of oxygen increased (P <0.01) and the pH increased (P <0.01) . Conclusion Non-invasive ventilation has a good therapeutic effect on patients with AECOPD and pulmonary encephalopathy, which is worthy of clinical promotion.