论文部分内容阅读
目的探讨溃疡性结肠炎(UC)采用微生态制剂治疗的效果。方法随机将100例UC患者分为两组,实验组使用美沙拉嗪缓释颗粒联合微生态制剂美常安,对照组使用美沙拉嗪缓释颗粒,在治疗前后进行组织学检查,并进行组织学严重程度分级计分,治疗3个疗程后评价临床疗效。结果治疗后两组组织学的严重程度分级计分显著下降,和治疗前比较差异具有统计学意义(t=4.634、2.547,P=0.000、0.004<0.01);两组相比明显下降(t=4.714,P=0.003<0.01)。治疗组(96.0%)的临床有效率高于对照组(82.0%),两组相比差异具有统计学意义(χ2=6.346,P=0.044<0.05)。结论微生态制剂美常安是治疗UC的一种有效的治疗方法,值得临床推广应用。
Objective To investigate the effect of using probiotics in the treatment of ulcerative colitis (UC). Methods 100 cases of UC patients were randomly divided into two groups, the experimental group with mesalazine sustained release particles combined with probiotics beauty, the control group with mesalazine sustained-release particles, before and after treatment for histological examination, and histology Severity score grading, evaluation of clinical efficacy after 3 courses of treatment. Results After treatment, the grading scores of histological severity decreased significantly in both groups (t = 4.634,2.547, P = 0.000,0.004 <0.01), and there was a significant difference between the two groups (t = 4.714, P = 0.003 <0.01). The clinical effective rate of the treatment group (96.0%) was higher than that of the control group (82.0%), the difference was statistically significant (χ2 = 6.346, P = 0.044 <0.05). Conclusion Microbiocidin is an effective treatment for UC, which is worthy of clinical application.