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本文报道运用家犬制备急性热病伤阴红舌证动物模型的实验方法及其应用的经验，结果表明：用腹腔内注射大量大肠杆菌引发急性腹腔内感染，同时以禁食水、利尿脱水法可以成功地制成家犬热病伤阴红舌证的模型，并以舌象、血生化，以及舌组织的扫描电镜和透射电镜变化作为指标进行定时的动态观察，对复方五参冲剂的药效机理进行了实验研究，所得结果为复方五参冲剂对治疗热病伤明红舌证的临床经验提供了确切的实验论据。
This article reports the experimental method and its application experience of domestic dogs in the preparation of animal models of acute febrile sera from Tongue Red Tongue. The results show that: a large number of E. coli intraperitoneal injection induced acute intraperitoneal infection, fasting water, diuretic dehydration The model of domestic dog can be made successfully, and the tongue, blood biochemical, and tongue tissue scanning electron microscopy and transmission electron microscopy were used as indicators for dynamic observation of timing, the effect of compound Wushen granules Effect mechanism of the experimental study, the results obtained for the compound Wushen agent on the treatment of fever, the Ming red tongue syndrome clinical experience provided an exact experimental argument.