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目的分析2012-2015年张家港市疑似预防接种异常反应(AEFI)的发生情况和特征,评价系统运行情况,以科学指导今后开展AEFI监测工作。方法通过AEFI信息管理系统收集2012-2015年报告的个案数据,采用描述性流行病学研究方法进行分析。结果 2012-2015年张家港市报告AEFI病例1 146例,报告发生率64.55/10万;其中一般反应占94.07%,异常反应占5.58%。男女性别比为1.45∶1,90.40%的AEFI都发生在24 h内;报告数位居前三位的疫苗分别是百白破、白破和麻风疫苗;临床诊断以发热/红肿/硬结为主,占84.64%。结论 AEFI监测系统运行情况正常,可探索开展主动监测,进一步提高全市AEFI监测的质量。
Objective To analyze the occurrence and characteristics of suspected AEFI in Zhangjiagang City from 2012 to 2015, evaluate the operation of the system and guide the future AEFI monitoring with scientific guidance. Methods Case data from the 2012-2015 report were collected through the AEFI Information Management System and analyzed using descriptive epidemiological methods. Results A total of 1 146 AEFI cases were reported in Zhangjiagang City from 2012 to 2015, with a reported incidence of 64.55 / 100 000, of which 94.07% were general reactions and 5.58% were abnormal reactions. AEFI of 1.45:1 and 90.40% were found within 24 hours. The top three vaccines reported were Baibaban, Baibu and Leprosy respectively. The clinical diagnosis was mainly fever / inflamed / induration , Accounting for 84.64%. Conclusion The operation of AEFI monitoring system is normal. Proactive monitoring can be explored to further improve the quality of AEFI monitoring in the city.