本文采用免疫组化法,探讨增殖细胞核抗原(PCNA)在宫颈炎、宫颈上皮不典型增生、宫颈原位癌及浸润癌中的表达,分析临床和病理学意义。选择宫颈炎、上皮不典型增生、宫颈原位癌、宫颈浸润癌共80例。PCNA的阳性表达在宫颈炎、宫颈上皮不典型增生,原位癌和浸润癌中呈明显递增趋势,并根据浸润癌的分化程度及浸润深度,PCNA阳性表达增强,因而PCNA可估计肿瘤的恶性潜能及判断预后。 In this paper, the expression of proliferating cell nuclear antigen (PCNA) in cervicitis, atypical hyperplasia of cervical epithelium, cervical carcinoma in situ and invasive carcinoma were studied by immunohistochemistry, and the clinical and pathological significance was analyzed. Select cervicitis, epithelial dysplasia, cervical carcinoma in situ, a total of 80 cases of cervical cancer. The positive expression of PCNA in cervicitis, cervical epithelial dysplasia, carcinoma in situ and invasive carcinoma showed a clear trend, and according to the degree of invasion and invasive depth, PCNA positive expression increased, so PCNA can estimate the malignant potential of the tumor And determine the prognosis.