论文部分内容阅读
目的:探讨女性高危型人乳头瘤病毒(HPV)感染的高峰年龄、感染阳性率及感染者的宫颈病理学改变。方法:以2008年5月～2009年4月于新疆维吾尔自治区乌鲁木齐市妇幼保健院复检时接受高危型HPV-DNA检查者为研究对象,对HPV-DNA阳性患者进行阴道镜检查、活检及病理检查。结果:该组人群共计3 282人次。高危型HPV-DNA阳性752例,阳性率22.9%。阴道镜活检615例,病理检查为慢性炎症者455例(73.98%);宫颈上皮内瘤样病变(CIN)157例(25.52%),其中CINⅠ121例、CINⅡ25例、CINⅢ11例;宫颈癌3例。结论:HPV阳性者CIN患病率明显高于普通人群,故对于高危型HPV感染者应尽量行阴道镜检查,可疑部位取活检,并进行定期随访。
Objective: To investigate the peak age of women with high-risk HPV infection, the positive rate of infection and cervical pathological changes in infected persons. Methods: From May 2008 to April 2009 in Urumqi, Xinjiang Uygur Autonomous Region of MCH re-examination of patients receiving high-risk HPV-DNA as the research object, HPV-DNA-positive patients colposcopy, biopsy and pathology an examination. Results: This group of people totaled 3,282. High-risk HPV-DNA positive 752 cases, the positive rate of 22.9%. Colposcopy biopsy in 615 cases, pathological examination for chronic inflammation in 455 cases (73.98%); Cervical intraepithelial neoplasia (CIN) 157 cases (25.52%), of which CINI1l1 cases, CINII25 cases, CINIII11 cases; Conclusion: The prevalence of CIN in HPV positive patients is significantly higher than that in the general population. Therefore, colposcopy should be performed for high risk HPV infection, suspicious sites for biopsy and regular follow - up.