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对7例肾移植术后加速期排异反应激素冲击治疗无效的患者作血浆置换治疗,结果6例排异逆转,1例失败。我们的体会是:对于体液免疫为主的血管型加速期排异,血浆置换疗效肯定,但应在排异发生的早期使用,配合适当的免疫抑制疗法。置换液胶体补充应以白蛋白为主,尽量不补血浆。应加强主持疗法,预防感染,对于术前群体反应抗体阳性、排异时合并急性肾小管坏死,则血浆置换疗效差。
Seven cases of renal transplant patients with accelerated response to hormone replacement therapy for patients without plasma replacement therapy, the results of 6 cases of reversal of rejection, 1 case of failure. Our experience is: for the humoral immune-based accelerated vascular exclusion, plasma replacement positive effect, but should be used in the early rejection, with appropriate immunosuppressive therapy. Replacement fluid colloid should be albumin-based, try not to make plasma. Should strengthen the host therapy, prevention of infection, for preoperative group reaction antibody positive, rejection with acute tubular necrosis, the poor plasma exchange.