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目的观察经鼻内镜下视神经管减压术联合复方樟柳碱注射液患侧颞浅动脉旁皮下注射治疗外伤性视神经损伤的疗效。方法外伤性视神经损伤63例(63只眼),随机分成经鼻内镜视神经管减压术联合复方樟柳碱患侧颞浅动脉旁皮下注射组(治疗组)33只眼,单纯视神经管减压术组(对照组)30只眼。全部患者均给予血管扩张药物和神经营养药物,急性期给予大剂量皮质类固醇、甘露醇。结果疗效的主要观察指标是视力。治疗组有效率78.79%,对照组有效率50%。两组比较显示:经鼻内镜视神经管减压术联合复方樟柳碱组疗效明显优于对照组,差异有显著性(x~2=5.48,P<0.05)。结论经鼻内镜视神经管减压术联合复方樟柳碱注射液患侧颞浅动脉旁皮下注射治疗外伤性视神经损伤是一种可供选择的、患者易接受的、创伤小、并发症及毒副作用少的有效治疗手段。
Objective To observe the curative effect of transnasal endoscopic optic nerve canal decompression combined with compound anisodine injection on the superficial temporal artery subcutaneous injection for traumatic optic nerve injury. Methods Totally 63 eyes (63 eyes) with traumatic optic nerve injury were randomly divided into three groups: 33 eyes (32 eyes) treated by endoscopic optic nerve canal decompression combined with compound anisodine ipsilateral subperiosteal injection (treatment group) Pressure surgery group (control group) 30 eyes. All patients were given vasodilators and neurotrophic drugs, given a high dose of corticosteroids, mannitol during the acute phase. Results The main outcome measure of efficacy was visual acuity. In the treatment group, the effective rate was 78.79% and in the control group, the effective rate was 50%. Comparisons of the two groups showed that the endoscopic optic canal decompression combined with compound anisodine was superior to the control group, the difference was significant (x ~ 2 = 5.48, P <0.05). Conclusion Transnasal endoscopic optic nerve canal decompression combined with compound anisodine injection in the affected side of the superficial temporal artery for subcutaneous injection of traumatic optic nerve injury is an alternative, the patient is easy to accept, trauma, complications and toxicity Less side effects of effective treatment.