Review:Anticancer effects of Chinese herbal medicine,science or myth?

来源 :Journal of Zhejiang University Science(Life Science) | 被引量 : 0次 | 上传用户:wuzhen16885168
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Currently there is considerable interest among oncologists to find anticancer drugs in Chinese herbal medicine (CHM). In the past, clinical data showed that some herbs possessed anticancer properties, but western scientists have doubted the scientific validity of CHM due to the lack of scientific evidence from their perspective. Recently there have been encouraging results, from a western perspective, in the cancer research field regarding the anticancer effects of CHM. Experiments showed that CHM played its anticancer role by inducing apoptosis and differentiation, enhancing the immune system, inhibiting angiogenesis, reversing multidrug resistance (MDR), etc. Clinical trials demonstrated that CHM could improve survival, increase tumor response, improve quality of life, or reduce chemotherapy toxicity, although much remained to be determined regarding the objective effects of CHM in human in the context of clinical trials. Interestingly, both laboratory experiments and clinical trials have demonstrated that when combined with chemotherapy, CHM could raise the efficacy level and lower toxic reactions. These facts raised the feasibility of the combination of herbal medicines and chemotherapy, although much remained to be investigated in this area. Currently the is considerable interest among oncologists to find anticancer drugs in Chinese herbal medicine (CHM). In the past, clinical data showed that some herbs possessed anticancer properties, but western scientists have doubted the validity validity of CHM due to the lack of scientific evidence Recently there have been encouraging results, from a western perspective, in the cancer research field regarding the anticancer effects of CHM. Experiments showed that CHM played its anticancer role by inducing apoptosis and differentiation, enhancing the immune system, inhibiting angiogenesis, reversing multidrug resistance (MDR), etc. Clinical trials of that CHM could improve survival, increase tumor response, improve quality of life, or reduce chemotherapy toxicity, although much more to be determined regarding the objective effects of CHM in human in the context of clinical trials. Interestingly, both laboratory experiments and clinical trials have demonstrated that when combined with chemotherapy, CHM could raise the feasibility level of the combination medicines and chemotherapy, but much remained to be investigated in this area.
其他文献
内源性阿片肽系统(e n d o-genous opioid system)有参与疼痛过程的调节、对应激的反应以及止痛治疗的作用。最近人体影像学显示其对内脏疼痛有显著的紧张调节作用,从而提出
目的 探讨小剂量白细胞介素-2(IL-2)腔内注射对恶性胸腔积液免疫细胞影响及临床疗效综合评价.方法 明确诊断的恶性胸腔积液患者20例.胸腔内注射小剂量IL-2(20万U/100ml),每周2次,连续4周.比较治疗前与治疗后2周胸腔积液肿瘤浸润树突状细胞(TIDC)和肿瘤浸润T淋巴细胞(TIL)亚群的变化,并观察治疗后4周临床缓解率及卡氏评分的变化.结果 治疗前恶性胸腔积液中S100+TIDC比例
Background: Heat shock protein (HSP) 105 is a 105-kDa protein, recently discovered by serological analysis of recom-binant cDNA expression libraries prepared fr
冶炼锌,可能会使镉元素泄漏到周围的环境中,镉是一种常见的工业污染物。据发表在《柳叶刀肿瘤学》(LancetOncology)杂志上的一篇研究论文,生活在含镉的环境中会增加患癌症的
PURPOSE: Recent studies have shown that the type 1/2 CD4+T cell (Th1/Th2) balance shifts toward Th2 dominance in cancer-bearing state or by surgical stress. Per
Background: Success of chemotherapy and alleviation of pain are frequently less than optimal in pancreatic cancer patients, leading to increasing interest in ne
病人男,47岁.胸闷、心悸20余天.查体:心率94次/min,血压85/65mmHg(11.3/8.6 kPa);面部水肿,颈静脉怒张;心音低钝.心电图示左室低电压,部分导联ST-T段压低.心脏彩色超声见右心房内位于静脉窦壁前方、卵圆窝之后上方由右房顶至右房外侧壁处4处中等回声光团,大小分别为2.01 cm×1.20cm、1.95cm×2.49cm、2.43 cm×2.90cm、1.49cm× 1
约翰·卡普斯在《久经考验的广告术》书中。记述了一项重大的观察.他发现不同诉求策略的广告,效果可以相差19.5倍。从我多年的广告与营销业经验看来,我认为他说得一点不错。
淋巴结密度指阳性淋巴结数与清扫淋巴结总数的比值。为评估淋巴结密度在根治性膀胱切除及术后辅助化疗中的价值,作者回顾分析了1993-2003年行膀胱切除术的150例淋巴结阳性但
央视重大活动报道所提供的创意性投放空间非常大,投放效果好不好关键在于企业能否有意识、有计划地把重大活动的广告价值挖掘充分。 CCTV major events reported the delive