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新生儿黄疸是新生儿期常见疾病之一,由多种原因所致,发病率近年有上升趋势,占住院新生儿的首位,高达30%~50%。过高的胆红素可以透过细胞膜进入细胞内干扰细胞的代谢功能,引起脑细胞功能代谢紊乱,严重者可产生胆红素脑病(核黄疸),导致严重后遗症,甚至死亡,对社会和家庭造成极大危害[1]。近年来微生态制剂在新生儿黄疸中的应用受到广泛关注。微生态制剂可以有效调节菌群平衡,促进新生儿肠道正常菌群的定植;可以降低肠腔内β-葡萄糖醛酸苷酶活性,
Neonatal jaundice is one of the most common neonatal diseases. It is caused by many causes. The incidence of neonatal jaundice has been on the rise in recent years, accounting for 30% to 50% of the newborns in the hospital. Too high bilirubin can enter the cell through the cell membrane to interfere with the metabolic function of cells, causing metabolic disorders of brain cells function, severe cases can produce bilirubin encephalopathy (kernicterus), leading to serious sequelae, and even death, to the community and family Caused great harm [1]. In recent years, the application of probiotics in neonatal jaundice has received widespread attention. The probiotics can effectively regulate the flora balance and promote the colonization of the normal intestinal flora of the newborn, reduce the activity of β-glucuronidase in the intestine,