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目的:比较埃索美拉唑与奥美拉唑治疗反流性食管炎的临床疗效。方法:选取120例在我院就诊的反流性食管炎患者,随机分为观察组(埃索美拉唑)和对照组(奥美拉唑),每组60例。对比两组的临床疗效。结果:观察组总有效率显著高于对照组(P<0.05)。治疗后两组症状评分均显著低于治疗前(P<0.05),且观察组症状评分显著低于对照组(P<0.05)。结论:埃索美拉唑临床治疗反流性食管炎的疗效优于奥美拉唑,将更能有效缓解反流性食管炎患者的临床症状,是治疗反流性食管炎的首选质子泵抑制剂,值得临床推广。
Objective: To compare the clinical efficacy of esomeprazole and omeprazole in the treatment of reflux esophagitis. Methods: 120 patients with reflux esophagitis treated in our hospital were randomly divided into observation group (esomeprazole) and control group (omeprazole), 60 cases in each group. Compare the clinical efficacy of the two groups. Results: The total effective rate in observation group was significantly higher than that in control group (P <0.05). After treatment, the symptom scores of both groups were significantly lower than those before treatment (P <0.05), and symptom score of the observation group was significantly lower than that of the control group (P <0.05). Conclusion: Esomeprazole is superior to omeprazole in the clinical treatment of reflux esophagitis, which will be more effective in relieving the clinical symptoms of reflux esophagitis and is the first choice of proton pump inhibition in treating reflux esophagitis Agent, it is worth clinical promotion.