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目的探讨多项目联合检测在炎性胸水和恶性胸水中的诊断与鉴别诊断价值。方法采用放射免疫检测技术,检测炎性胸水和恶性胸水中癌胚抗原、β2微球蛋白、铁蛋白的含量,同时检测血液中的含量,并用SPS之S统计软件进行统计学分析处理。结果恶性胸水中CEA、SF显著高于炎性胸水,P<0.01;而β2-MG则低于炎性胸水,P<0.01;恶性胸水、炎性胸水患者血清中CEA、β2-MG均高于正常组,而SF无差别。结论CEA、β2-MG、SF的联合检测有助于恶性胸水与炎性胸水的诊断和鉴别诊断。
Objective To investigate the diagnostic value of multi-item combined detection in the diagnosis of inflammatory pleural effusion and malignant pleural effusion. Methods Radioimmunoassay was used to detect the content of carcinoembryonic antigen, β2 microglobulin and ferritin in inflammatory pleural effusion and malignant pleural effusion. Meanwhile, the content of ferritin in blood was detected by SPSS statistical software. Results The levels of CEA and SF in malignant pleural effusion were significantly higher than those in inflammatory pleural effusion, P <0.01; while β2-MG was lower than that in inflammatory pleural effusion, P <0.01; CEA and β2-MG in serum were higher in malignant pleural effusion and inflammatory pleural effusion Normal group, while SF no difference. Conclusion The combined detection of CEA, β2-MG and SF is helpful for the diagnosis and differential diagnosis of malignant pleural effusion and inflammatory pleural effusion.