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本文介绍了 86例不同程度一氧化碳 ( CO)中毒患者在进行高压氧治疗前后对其血浆中分子 ( MMS)、肌酸激酶心型同工酶 ( CK— MB)进行了动态观察。 CO中毒患者血浆 MMS含量明显升高 ,高峰值为 34 1± 62 u/ dl,对照组为 2 2 8± 15u/ dl;显示心肌损伤的酶 CK— MB,也存在明显差异 ,死亡组峰值为 99± 10 1IU/ L ,而存活组为 4 4± 2 2 u/ dl,与中毒程度及 MMS含量呈正相关。高压氧治疗组 MMS下降的幅度大于一般疗法组 ,且恢复正常时间也短 ,一般在 10日左右恢复正常。碳氧血红蛋白 ( Hb CO)浓度在中毒当时最高 ,脱离现场后必然有所下降。因此 ,同时检测 MMS对诊断和衡量 CO中毒程度、指导治疗和判定预后具有重要意义。
This article describes the 86 patients with varying degrees of carbon monoxide (CO) poisoning before and after hyperbaric oxygen therapy in the plasma of the molecule (MMS), creatine kinase cardiac isozyme (CK-MB) were observed. The concentration of MMS in plasma of CO poisoning patients was significantly higher than that of control group (34 1 ± 62 u / dl, control group, 228 ± 15u / dl). There was also a significant difference in CK- 99 ± 10 1 IU / L, while survival group was 44 ± 2 2 u / dl, which was positively correlated with the degree of poisoning and MMS content. The magnitude of MMS decline in hyperbaric oxygen therapy group was larger than that in general therapy group, and the time to normal recovery was also short, and returned to normal after 10 days. The concentration of carboxyhemoglobin (Hb CO) was the highest at the time of poisoning, which inevitably declined after leaving the scene. Therefore, simultaneous detection of MMS for the diagnosis and measurement of CO poisoning degree, guiding treatment and prognosis of great significance.