胃十二指肠溃疡是常见的消化道疾病。“无酸、无溃疡”一直被视为指导治疗的理论依据 ,多年来采用各类药物用以碱化胃腔、保护胃黏膜屏障作为主要治疗手段。上个世纪 80年代对幽门螺杆菌的发现 ,拓宽了对消化性溃疡的认识 ,实践证明有效地清除幽门螺杆菌感染并联合抑酸药物会加 Gastroduodenal ulcer is a common gastrointestinal disease. “Acid-free, non-ulcer” has long been regarded as the theoretical basis for guiding the treatment. For many years, various types of drugs have been used to alkalinate the gastric cavity and protect the gastric mucosal barrier as the main treatment. 80s of last century, the discovery of Helicobacter pylori, broaden the understanding of peptic ulcer, the practice proved effective in removing Helicobacter pylori infection combined with acid-suppressing drugs will add