患者,男,52岁,工人,青海籍。全身肌肉僵硬及疼痛十二天入院。发病前曾受凉,感全身不适,四肢肌肉痉挛性抽搐,并渐加重,继而出现肌肉僵硬,活动不便,强行活动时肌肉疼痛、酸痛剧烈。四肢呈伸直位,伸屈活动均受限,不能转头及张口,吞咽困难,呈进行性加重。食欲、睡眠均可。体检;面部表情呆板,头僵硬而不易搬动,腹肌强直如板状,无压痛及反跳 Patient, male, 52 years old, worker, Qinghai membership. Whole body muscle stiffness and pain twelve days admitted. Before the onset of a cold, feeling unwell, limb spasm and convulsions, and gradually heavier, and then there muscle stiffness, inconvenience of activity, forced muscle ache, soreness. Extensions were straight limbs, flexion and extension activities are limited, can not turn around and mouth, swallowing difficulties, were progressive increase. Appetite, sleep can be. Physical examination; dull facial expression, head stiff and not easy to move, abdominal muscles such as plate-like, no tenderness and rebound