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目的总结肥胖与胃癌关系的研究进展。方法计算机检索Pub Med、Medline、EMBASE、Cochrane图书馆、CNKI及万方数据库获取肥胖与胃癌关系的文献资料,就近几年关于肥胖与胃癌的发生、肥胖对手术效果及预后的影响的研究现状进行综述。结果肥胖增加了机体患食管胃结合部腺癌(AEG)的风险。此外,肥胖增加了胃癌根治手术操作的难度,增加了围手术期并发症的发生风险,但并不影响远期手术效果。尽管体质量指数与胃癌患者预后的关系目前还不清楚,但多数研究显示肥胖胃癌患者的远期预后优于非肥胖患者。结论肥胖与胃癌的关系十分复杂,目前尚无定论,通过健康生活方式控制体质量有望降低AEG的发病率。
Objective To summarize the research progress of the relationship between obesity and gastric cancer. Methods The literature about PubMed, Medline, EMBASE, Cochrane Library, CNKI and Wanfang database was searched by computer. The current research status of obesity and gastric cancer and the effect of obesity on the surgical outcome and prognosis were reviewed Summary. Results Obesity increased the risk of esophageal-gastric-adenocarcinoma (AEG) in the body. In addition, obesity increases the difficulty of radical operation of gastric cancer, increases the risk of perioperative complications, but does not affect the long-term surgical results. Although the relationship between body mass index and the prognosis of patients with gastric cancer is unclear, most studies have shown that the long-term prognosis of patients with obesity is superior to that of non-obese patients. Conclusion The relationship between obesity and gastric cancer is very complicated. There is no conclusion yet. The control of body mass through healthy lifestyles is expected to reduce the incidence of AEG.