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目的探讨头孢曲松的不良反应(ADR)及相关性分析。方法通过检索2001年1月至2011年6月国内发表的有关头孢曲松ADR文献报道,并进行统计分析。结果 ADR发生率为3.12%,涉及多个器官和(或)系统,全身性损害中以过敏性休克多见,并致死7例。结论应用头孢曲松所致不良反应,大剂量、长时间使用时应警惕过敏反应、血液系统和肝胆系统损害。
Objective To investigate the adverse reaction (ADR) and correlation analysis of ceftriaxone. Methods Retrieved from January 2001 to June 2011 published in the literature about ceftriaxone ADR, and statistical analysis. Results The incidence of ADR was 3.12%, which involved multiple organs and / or systems. Anaphylactic shock was more common in systemic injury and was fatal in 7 cases. Conclusion Application of ceftriaxone adverse reactions, high doses, long-term use should be alert to allergic reactions, hematological and hepatobiliary system damage.