黄体酮系妇科常用药,于五十年代初虽有合成孕激素代替肌注黄体酮,但因其有溶黄体作用,使子宫内膜的腺体和间质发育不同步而不利于孕卵种植,还有致性发育异常等缺点,限制其广泛使用。天然黄体酮肌注也有其缺点。本文应用黄体酮阴道栓(简称药栓)作孕激素试验和黄体不健的补充治疗,获得满意结果。观察用药栓前后血黄体酮浓度变化和肌注黄体酮自身对照,证实药栓经阴道吸收良好,能避免注射的痛苦及减少肝脏对药物破坏。此外,用药方便,可由病人自己给药 Progesterone gynecology gynecological commonly used drugs, although in the early fifties synthetic progesterone instead of intramuscular injection of progesterone, but because of its role in the dissolution of luteal, endometrial glands and interstitial development is not synchronized and is not conducive to the development of pregnant eggs , As well as defects such as deregulated development, limiting its widespread use. Natural progesterone intramuscular injection also has its drawbacks. In this paper, progesterone vaginal suppository (referred to as drug suppository) for progestin test and corpus luteum supplement treatment, obtain satisfactory results. Observed before and after administration of suppositories blood progesterone concentration changes and intramuscular injection of progesterone self-control, confirmed by the vaginal absorption of suppositories good, to avoid the pain of injection and reduce the liver damage to drugs. In addition, medication is convenient and can be administered by the patient himself