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Asymmetric hydrogenation of (6-methoxyl-2-naphthyl)-2-acrylic acid catalyzed by cinchona modified Pd(0)-a-FeOOH was reported and ee抯 of (S)-(+)-2-(6′-methoxyl-2-naphthyl) propionic acid ((S)-(+)-naproxen) up to 98% was achieved firstly.
Asymmetric hydrogenation of (6-methoxyl-2-naphthyl) -2-acrylic acid catalyzed by cinchona modified Pd (0) -a-FeOOH was reported and ee’s of (S) -2-naphthyl) propionic acid ((S) - (+) - naproxen) up to 98% was achieved.