目的观察盐酸特比萘芬阴道泡藤片联合乳杆菌活菌治疗复发性外阴阴道假丝酵母菌病(RVVC)的临床疗效。方法将164例RVVC患者随机分为3组,治疗组(57例)予盐酸特比萘芬阴道泡藤片联合乳杆菌活菌胶囊治疗,对照1组(50例)仅予盐酸特比萘芬阴道泡藤片治疗,对照2组(57例)仅予硝酸咪康唑阴道胶囊治疗。3组患者均随访1年。结果 1年后,治疗组、对照1组和对照2组有效率分别为89.47%,80.00%,73.68%,复发率分别为10.00%,25.64%和26.19%,3组的有效率和复发率比较,差异均有统计学意义(P均<0.05)。结论盐酸特比萘芬阴道泡藤片联合乳杆菌活菌治疗RVVC的疗效好,复发率低。 Objective To observe the clinical efficacy of terbinafine hydrochloride vaginal infusion combined with Lactobacillus to treat recurrent vulvovaginal candidiasis (RVVC). Methods One hundred and sixty-four patients with RVVC were randomly divided into three groups. The treatment group (57 cases) received terbutaline hydrochloride combined with Lactobacillus live capsules, while the control group 1 (50 cases) received only terbinafine hydrochloride Vaginal bubo treatment, control 2 (57 cases) only to miconazole nitrate vaginal capsule treatment. Three groups of patients were followed up for 1 year. Results After 1 year, the effective rates of the treatment group, the control group 1 and the control group 2 were 89.47%, 80.00% and 73.68%, respectively, and the recurrence rates were 10.00%, 25.64% and 26.19%, respectively , The differences were statistically significant (P all <0.05). Conclusion Terbinafine hydrochloride vaginal bubble vine tablets combined with viable Lactobacillus treatment of RVVC good effect, low recurrence rate.