由于氟原子的特殊性质,有机物中引入氟元素可以显著提高其脂溶性、稳定性以及生物活性.正因为如此,近几十年来,有机含氟化合物越来越多地出现在医药、农药以及材料等领域.与传统的氟化反应相比,通过碳氢键活化构建碳氟键是最有效直接地引入氟原子的手段,也是目前研究的热点.尽管如此,当前已有的为数不多的几例碳氢键 Due to the special nature of fluorine atoms, the introduction of fluorine into organic matter can significantly increase its lipid solubility, stability and biological activity, and as a result, organic fluorine compounds are increasingly appearing in pharmaceuticals, pesticides and materials in recent decades Etc. Compared with the traditional fluorination reaction, it is the most effective and direct method to introduce fluorocarbon bond through the activation of carbon-hydrogen bond, which is also the hot point of current research.Nowadays, there are only a few Example of carbon-hydrogen bond