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目的:对不同孕周早发型重度子痫前期妊娠孕妇预后、并发症和围生儿结局进行分析,为临床提供依据。方法:随机选择早发型重度子痫前期患者78例,根据孕周不同随机分为两组,A组(<32周)37例,B组(32~34周)41例。分析两组患者基本情况、并发症和母婴结局。结果:B组入院孕周为(33.18±1.22)周,高于A组[(29.62±1.80)周],两组比较,差异有统计学意义(P<0.05);A组治疗时间为(15.35±2.14)天,多于B组[(9.28±1.53)天],两组比较,差异有统计学意义(P<0.05);B组孕妇分娩前胎盘早剥、心衰、腹水、肝肾能损害和HELLP综合征均低于A组,两组比较,差异有统计学意义(P<0.05);B组的剖宫产、阴道顺产和引产与A组比较,差异有统计学意义(P<0.05);B组新生儿窒息和围生儿死亡2例均低于A组,两组比较,差异有统计学意义(P<0.05)。结论:不同孕周是影响早发型重度子痫前期孕妇、胎儿及新生儿病死率的主要因素,孕周越早,孕妇并发症越多、存活率越低,围产儿预后越差。
OBJECTIVE: To analyze the prognosis, complications and perinatal outcome of pregnant women with early-onset severe pre-eclampsia in different gestation weeks to provide evidence for clinical practice. Methods: Seventy-eight patients with early-onset severe preeclampsia were randomly divided into two groups according to gestational ages: group A (n = 32), group B (n = 41), and group B (n = 32 to 34) Analysis of two groups of patients with basic information, complications and maternal and infant outcomes. Results: The gestational age in group B was (33.18 ± 1.22) weeks, which was significantly higher than that in group A [(29.62 ± 1.80) weeks], the difference was statistically significant (P <0.05) ± 2.14) days, more than those in group B [(9.28 ± 1.53) days]. There was a significant difference between the two groups (P <0.05). In group B, preeclampsia, heart failure, ascites, The damage and HELLP syndrome were lower in group A than in group A, the difference was statistically significant (P <0.05). The difference between group B in cesarean section, vaginal delivery and induced abortion was statistically significant (P < 0.05). Two cases of neonatal asphyxia and perinatal death in group B were lower than that in group A, the difference was statistically significant (P <0.05). CONCLUSION: Different gestational weeks are the main factors that influence the mortality rate of pre-term severe pre-eclampsia in pregnant women, fetus and newborn. The earlier gestational weeks, the more complications of pregnant women, the lower the survival rate and the worse the prognosis of perinatal children.