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目的探讨晚发支气管哮喘与慢性阻塞性肺疾病(COPD)肺功能及气道反应性比。方法晚发支气管哮喘与慢性阻塞性肺疾病患者各45例,检测两组患者,肺功能指标及气道反应性比。结果两组患者1秒钟用力呼气容积(FEV1)、最大呼气流量(PEF)、最大呼气中段流量(MMEF)、气道阻力(Raw1)、Raw2)差异有统计学意义(P<0.05);COPD组肺气肿发生率高于晚发哮喘组(P<0.05)。结论肺功能检查与气道反应性检测,对于晚发支气管哮喘与慢性阻塞性肺疾病准确诊断治疗具有重要作用,可以作为制定治疗方案的依据,临床应用价值较高。
Objective To investigate the pulmonary function and airway responsiveness of late-onset bronchial asthma and chronic obstructive pulmonary disease (COPD). Methods Forty-five patients with late-onset bronchial asthma and chronic obstructive pulmonary disease were enrolled in this study. The pulmonary function and airway responsiveness were compared between the two groups. Results The differences of FEV1, PEF, MMEF, Raw1 and Raw2 between the two groups were statistically significant (P <0.05 ). The incidence of emphysema in COPD group was higher than that in late-onset asthma group (P <0.05). Conclusion Pulmonary function tests and airway reactivity tests play an important role in the accurate diagnosis and treatment of late-onset bronchial asthma and chronic obstructive pulmonary disease, and can be used as the basis for the development of treatment programs and have high clinical value.