业已证明,基质成分与乳腺上皮细胞行为的调节相关,但尚不知其对人乳腺癌细胞的生长发育是否有影响。为此,作者用裸鼠进行体内实验。所用的细胞是MCF 7人乳腺癌细胞和取自14例女性乳腺组织标本(主要为乳腺癌和乳腺纤维瘤,取材包括癌和未受累的乳腺组织)的成纤维细胞。 It has been shown that matrix components are related to the regulation of mammary epithelial cell behavior, but it is not known whether it has an effect on the growth and development of human breast cancer cells. For this purpose, the authors used nude mice for in vivo experiments. The cells used were MCF 7 human breast cancer cells and fibroblasts taken from 14 female breast tissue specimens (mainly breast and fibrosarcoma, including tissues including cancerous and non-affected breast tissue).