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多数肝细胞癌(HCC)伴有肝硬化,预后较差。迄今为止,影响HCC患者的预后因素了解很少。作者等对206例经临床、生化、B超和病理检查证实的欧美国家患原发性肝癌者,男156例,女50例,平均年龄62.2±0.7岁(22~89岁),应用多变量分析方法研究影响HCC预后的因素。其中仅58例HCC进行各种治疗,包括肿瘤切除13例,化疗38例和肿瘤内酒精注射7例,其余148例仅作对症处理。本组病人的中位存活期3.3个月(0.1~65个月),23%患者存活一年以上。多变量分析表明,有9个独立因素与患者存活期有关,即
Most hepatocellular carcinoma (HCC) is associated with cirrhosis and has a poor prognosis. To date, little is known about the prognostic factors affecting HCC patients. The author et al. applied 206 multivariate analysis to 206 cases of primary liver cancer in European and American countries confirmed by clinical, biochemical, ultrasonographic, and pathological examinations, including 156 males and 50 females, with an average age of 62.2±0.7 (22-89 years). Analytical methods to study the factors affecting the prognosis of HCC. Among them, only 58 cases of HCC undergo various treatments, including 13 cases of tumor resection, 38 cases of chemotherapy and 7 cases of intratumoral alcohol injection, and the remaining 148 cases were treated only for symptomatic treatment. The median survival of this group of patients was 3.3 months (0.1 to 65 months), and 23% of patients survived for more than one year. Multivariate analysis showed that there are 9 independent factors that are related to the survival of patients, ie