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目的探讨O型孕妇血清中IgG抗A(B)效价与新生儿溶血病关系。方法随机抽取在2009年10月-2012年10月本院收治的夫妻血型不合、妊娠20周以上、进行产检的O型血孕妇923例,对其在孕期展开血清中IgG抗A(B)效价监测,而后统计新生儿溶血病的发生情况。结果本组孕妇血清IgG抗A(B)效价包括有:<1 64、1 64、1 128、≥1 256几个级别,新生儿溶血发生率分别为0.57%、8.22%、45.28%、84.00%。结论随着孕妇抗体效价的增加,新生儿溶血的发生率也随之增加,临床应给予关注。
Objective To investigate the relationship between serum IgG anti-A (B) titer and hemolytic disease of newborn in type O pregnant women. Methods Nine hundred and seventy-three O-pregnant women who were admitted to our hospital from October 2009 to October 2012 were enrolled in this study. Their serum levels of IgG anti-A (B) Price monitoring, and then statistics of neonatal hemolytic disease. Results The serum IgG anti-A (B) titers of pregnant women in this group included: <1 64,1 64,1 128, ≥1 256 levels, the incidence of hemolysis in neonates were 0.57%, 8.22%, 45.28%, 84.00 %. Conclusion With the increase of antibody titer in pregnant women, the incidence of hemolysis in neonates also increases, and clinical attention should be given.