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目的:探讨乌藤镇痛胶囊镇痛及活血化瘀作用。方法:小鼠尾尖压痛法探讨乌藤镇痛胶囊镇痛作用;大鼠皮下注射大量盐酸肾上腺素附加冰水浴造急性血瘀模型,观察其对急性血瘀模型大鼠血液流变学各指标的影响。结果:乌藤镇痛胶囊能显著提高物理刺激引起的小鼠痛阀;明显降低血瘀模型的大鼠全血(高切、低切)粘度、血浆高切粘度和全血还原粘度,也可显著降低血沉值、红细胞压积和血浆纤维蛋白原含量。结论:乌藤镇痛胶囊有明显的镇痛、活血化瘀作用。
Objective: To investigate the analgesic effect of Wu-teng analgesic capsule and the role of promoting blood circulation and removing blood stasis. Methods: The rat tail tenderness method was used to investigate the analgesic effect of WuTongZuoTong Capsule. A large amount of epinephrine hydrochloride was added into the rat subcutaneously to establish an acute blood stasis model. The changes of hemorheology indexes of acute blood stasis model rats were observed. Impact. Results: WuTouZeTong Capsule can significantly improve the physical stimulation of mice pain valve; significantly reduce blood stasis model rats whole blood (high shear, low shear) viscosity, plasma viscosity and whole blood viscosity reduction, but also Significantly reduced ESR, hematocrit and plasma fibrinogen content. Conclusion: Wu Teng analgesic capsule obvious analgesic, promoting blood circulation.