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癫癇猝死系指癫癇患者在发作期或发作间期突发的无法解释的死亡,其风险是普通人群的20余倍。癫癇猝死存在多种机制,与心功能的相关性研究是目前研究的重要课题。癫癇和心脏离子通道病共存的遗传易感性、自主神经功能异常、抗癫癇药物等相关因素导致的心功能异常易诱发癫癇患者发生心源性猝死,进一步了解癫癇猝死发生过程中的心脏病变相关机制能够为制定预防和治疗策略提供理论基础。
Epileptic sudden death refers to the unexplained death of an epileptic patient during an episode or interictal episode at a risk of more than 20 times greater than in the general population. Epilepsy sudden death exists a variety of mechanisms, and the correlation between cardiac function research is an important issue at present. Epilepsy and cardiac ion channel disease coexistence of genetic predisposition, autonomic dysfunction, anti-epileptic drugs and other related factors lead to cardiac dysfunction easily induced epilepsy patients with sudden cardiac death and further understanding of epilepsy during the occurrence of sudden cardiac death related mechanisms Can provide a theoretical basis for the formulation of prevention and treatment strategies.