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目的探索社区女性性工作者(female sex workers,FSWs)对暴露前药物预防艾滋病使用意愿及影响因素。方法采用横断面设计,在中山市镇区按分层整群抽样的方法,选取部分镇区FSWs进行问卷调查。内容包括一般人口学特征、艾滋病相关知识和态度、性行为特征、相关暴露史和改良口服暴露前预防药物接受性等。结果共调查277名FSWs,该人群对暴露前药物预防艾滋病干预措施的接受率为72.2%,消除共线性及校正年龄和民族后,多因素Logistic分析显示,可接受性的主要影响因素为药物免费(OR=15.00,P<0.001)、不坚持使用安全套(OR=2.51,P=0.024)、在婚或者同居(OR=2.19,P=0.037)、药物药理得分高(OR=1.13,P=0.014)、来自中低档娱乐场所。结论社区FSWs对暴露前药物预防艾滋病的可接受性较高,中低档娱乐场所的FSWs迫切需要新的艾滋病预防措施。
Objective To explore the willingness and influence factors of female sex workers (FSWs) on pre-exposure drug use to prevent AIDS. Methods The cross-sectional design was used to select the FSWs of some townships for questionnaire survey by stratified cluster sampling in Zhongshan Township. It includes general demographic characteristics, HIV-related knowledge and attitudes, sexual characteristics, history of exposure, and improvement of pre-op oral prophylaxis drug acceptance. Results A total of 277 FSWs were surveyed. The population acceptance rate of pre-exposure drugs for AIDS prevention was 72.2%. After eliminating collinearity and adjusting for age and ethnicity, multivariate Logistic analysis showed that the main influencing factors of acceptability were drug free (OR = 2.19, P = 0.037). The drug pharmacology scores were high (OR = 1.13, P = 0.014) in the cohabitation or cohabitation group (OR = ), From middle and low entertainment. Conclusions Community FSWs are more acceptable to pre-exposure drugs for AIDS prevention. FSWs in middle and low-end entertainment establishments urgently need new HIV prevention measures.