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背景与目的:提高乳腺癌疗效、延长患者生存期,关键在于早期诊断。而早期乳腺癌多为隐匿性,临床无法扪及,实验室检查也不能提供有效的检测方法,诊断困难。本研究旨在探寻有效的检查手段,以提高乳腺癌的早期诊断率。方法:选择钼靶照片发现有可疑恶性病变而临床未扪及肿块的患者24例,对每一病例进行计算机辅助钼靶立体定位,并分别行细针抽吸细胞学检查、粗针穿刺活检、病灶染色手术切除冰冻切片活检术,与术后病理对照。结果:本组细针抽吸细胞学检查、粗针穿刺活检和病灶染色手术切除冰冻切片检查的符合率分别为75%、92%和100%(P<0.05)。结论:计算机辅助钼靶立体定位病灶染色手术切除冰冻切片活检术是提高乳腺癌早期诊断率的理想诊断技术。
Background and Objective: To improve the efficacy of breast cancer and prolong the survival of patients, the key lies in the early diagnosis. The early stage of breast cancer are mostly occult, clinically impractical, laboratory tests can not provide an effective test, diagnosis is difficult. The purpose of this study is to explore effective means to improve the early diagnosis of breast cancer. Methods: Twenty-four patients with suspicious malignant lesions and no palpable tumor were selected for mammography. The computer-aided mammography stereotactic localization was performed in each case. Fine needle aspiration cytology, needle biopsy, Surgical resection of frozen sections of lesions biopsy, and postoperative pathological control. Results: The coincidence rates of fine needle aspiration cytology, gross needle biopsy and resection cryosection were 75%, 92% and 100% respectively (P <0.05). CONCLUSION: Computer-assisted stereotactic mammography is the ideal diagnostic technique to improve the early diagnosis rate of breast cancer.