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目的 观察科素亚(Losartan)与洛定新(Lotensin)的降压效果。方法 对应用科素亚与洛定新治疗的52例高血压患者,分别记录每日晨测血压和24h动态血压的变化,观察治疗效果。结果 科素亚和洛定新都有明显降压作用,但科素亚降低舒张压及增大降压的谷峰比率的效果优于洛定新(P<0.05)。结论 科素亚是一种安全有效的降压药。
Objective To observe the antihypertensive effects of Losartan and Lotensin. Methods Fifty-two hypertensive patients treated with Cozaar and Losodrine were respectively recorded daily morning blood pressure and 24h ambulatory blood pressure, and the therapeutic effect was observed. Results Both Cozaar and Luoding had a significant antihypertensive effect, but Cozaar was superior to Luodingxin in reducing the diastolic blood pressure and increasing the peak-to-peak ratio of antihypertensive drugs (P <0.05). Conclusion Cozaar is a safe and effective antihypertensive drug.