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选择基础促卵泡激素水平在正常范围(<10 IU/L),年龄≥35岁不孕症患者81例,应用促性腺激素释放激素拮抗剂GnRHanta(思则凯)结合促性腺激素超排方案进行89个周期超排卵治疗,根据获卵数判断卵巢反应性,分卵巢反应正常组和低反应组,探讨在月经周期第2d及周期第6d监测卵巢窦卵泡计数来预测卵巢低反应性的价值。结果显示:卵巢反应低下组在月经周期第2d及周期第6d测得的窦卵泡数均显著低于反应正常组。月经周期第6d的卵泡数的相关性较周期第2d的要好。这表明经阴道超声动态监测月经周期第2d及周期第6d的窦卵泡计数可提高GnRHanta方案超排卵治疗高龄不孕患者卵巢低反应的预测率,月经周期第6d的窦卵泡计数比周期第2d的有更好的预测价值。
81 patients with infertility ≥35 years of age who had the basal follicle stimulating hormone (FSH) in the normal range (<10 IU / L) and GnRHanta (ghrelin) combined with gonadotrophin regimen 89 cycles of superovulation treatment, according to the number of oocytes to determine ovarian response, subnormal ovarian response group and low response group, to explore in the menstrual cycle 2d and 6d cycle monitoring ovarian sinus follicle count to predict ovarian hyporesponse value. The results showed that the number of antral follicles measured on the 2nd day of the menstrual cycle and on the 6th day of the low ovarian response group was significantly lower than that of the normal reaction group. The correlation between the number of follicles on the 6th day of the menstrual cycle was better than that on the 2nd day of the cycle. This shows that transvaginal ultrasound dynamic monitoring of menstrual cycle 2d and 6d of the cycle of antral follicle count can improve the GnRHanta regimen superovulation treatment of elderly patients with low ovarian response to infertility prediction rate of 6d menstrual cycle of the antral follicle count than the cycle of 2d Have a better forecasting value.