检测121例高脂血症(其中高脂血症合并冠心病30例,合并高血压30例)和50例健康人的血清脂蛋白、载脂蛋白及10种微量元素。结果:镉、镍、铅、铝与血清TC,TG,LDL-C,apoB水平呈显著正相关关系,与HDL-C,HDL_2-C,HDL_3-C,apoA-Ⅰ水平呈显著负相关关系,而铬,锰,铁与血脂的相关性同以上结果相反。认为人体微量元素变化与高脂血症及其并发症的血脂水平有关,通过饮食等方法调整血清微量元素的总水平可作为高脂血症的防治措施之一。 Serum lipoprotein, apolipoprotein and 10 trace elements in 121 cases of hyperlipidemia (including 30 cases of hyperlipidemia with coronary heart disease and 30 cases of hypertension) and 50 healthy subjects were detected. Results: The levels of serum TC, TG, LDL-C and apoB were positively correlated with cadmium, nickel, lead and aluminum, and negatively correlated with HDL-C, HDL-C, HDL-3-C and apoA- The chromium, manganese, iron and blood lipids with the above results contrary. It is considered that the changes of trace elements in the human body are related to the blood lipid level of hyperlipidemia and its complications, and the total level of serum trace elements can be adjusted by diet and the like as one of the prevention and treatment measures of hyperlipidemia.