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The author investigated the antioxidant effect of irbesartan[2-butyl-3-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)· phenyl]phenyl}methyl)-1,3-diazaspiro[4.4]non-1-en-4-one], an angiotensin receptor blocker(ARB), on the oxidation of erythrocytes induced by 2,2-