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目的:对新生儿低血糖脑损伤的临床特征及预后进行探究。方法:收集我院诊治的新生儿低血糖脑损伤患儿共80例为观察组,并同期选择住院的新生儿低血糖无脑损伤的病例80例作为对照组。分析两组患儿的临床特征并进行比较分析。结果:两组患儿的一般情况,如平均胎龄、出生时平均体质量及首次发生低血糖的时间均无显著性差异(P>0.05),观察组平均最低血糖值明显低于对照组的平均最低血糖值(P<0.01),低血糖持续的时间显著长于对照组持续的时间(P<0.01)。对观察组患儿进行6个月随访,发生新生儿低血糖脑损伤造成而留有神经系统后遗症者有11例(13.75%),对照组未出现一例神经系统后遗症患儿。结论:新生儿低血糖患者临床表现重、低血糖持续时间长其临床预后较差,新生儿低血糖患者临床表现轻、低血糖持续时间短其临床预后较好。及早诊断、及时采取医疗措施纠正低血糖,以降低新生儿低血糖症及其脑损伤的发生。
Objective: To investigate the clinical features and prognosis of hypoglycemic brain injury in neonates. Methods: A total of 80 neonates with hypoglycemic brain injury who were diagnosed and treated in our hospital were selected as observation group. 80 neonates with hypoglycemia without brain injury who were hospitalized in the same period were selected as control group. The clinical features of the two groups were analyzed and compared. Results: There was no significant difference between the two groups (P> 0.05), such as average gestational age, average body mass at birth and first hypoglycemia (P> 0.05). The average minimum blood glucose of the observation group was significantly lower than that of the control group Mean low blood glucose (P <0.01), duration of hypoglycemia was significantly longer than the control group (P <0.01). A total of 11 children (13.75%) with neurological sequelae who had hypoglycemic brain injury in the observation group were followed up for 6 months. There was no neurological sequelae in the control group. Conclusion: The clinical manifestations of neonatal hypoglycemia patients with long duration of hypoglycemia, its clinical prognosis is poor, mild hypoglycemia in neonates with mild clinical manifestations, short duration of hypoglycemia, its clinical prognosis is good. Early diagnosis, timely medical measures to correct hypoglycemia, in order to reduce neonatal hypoglycemia and its occurrence of brain damage.