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目的探讨子宫内膜与卵巢双原发癌的临床病理特点、治疗和预后。方法回顾性分析12例子宫内膜与卵巢双原发癌,其中两个部位均为子宫内膜腺癌者8例,两个部位是两种完全不同的病理类型者4例。结果子宫内膜与卵巢双原发癌术前诊断困难,12例均经术后病理确诊。其特点为:卵巢肿瘤体积较小,平均7 cm;原发不孕比例高(40．7％);早期居多,两部位均为I期者8例(66．7％);病理类型以子宫内膜样癌最多见(66．7％)。所有病例均行手术和化疗,3年生存率为66．7％(8／12)。结论子宫内膜与卵巢双原发癌是有别于原发性子宫内膜癌或卵巢癌的一种特殊类型的肿瘤,一般发现早,预后较好。
Objective To investigate the clinicopathological characteristics, treatment and prognosis of endometrial and ovarian double primary carcinomas. Methods Retrospective analysis of 12 cases of endometrial and ovarian double primary cancer, two of which were endometrial adenocarcinoma in 8 cases, two parts are two completely different pathological types in 4 cases. Results Both endometrial and ovarian primary primary tumors were difficult to diagnose preoperatively, and all 12 cases were confirmed by postoperative pathology. It is characterized by a small volume of ovarian tumors (average 7 cm), high rate of primary infertility (40.7%), early stage (8 cases, 66.7% Endometrial carcinoma was the most common (66.7%). All cases underwent surgery and chemotherapy. The 3-year survival rate was 66.7% (8/12). Conclusions Dual primary endometrium and ovarian cancer is a special type of tumor distinct from primary endometrial cancer or ovarian cancer. Early detection and prognosis are generally better.