论文部分内容阅读
目的：研究氟脲嘧啶乳剂直肠内灌注治疗直肠癌对T细胞亚群的影响及加用中药后的免疫调理作用。方法：采用随机方法，分为中药化疗组及对照组，取术前第7天，术后第1、7、14、21、28天外周血，以单抗APAAP法测定T细胞亚群。采用t检验进行统计学处理。结果：两组比较：CD3+、CD4+、CD8+、CD4+／CD8+均于术后第7天以后有显著性差异（P0．05～0．001）。结论：中药可改善团单用氟脲嘧啶乳剂所至的细胞免疫抑制状态及临床症候，能显著地调理机体细胞免疫系统。
OBJECTIVE: To study the effects of intrarectal instillation of fluorouracil emulsion on rectal cancer on T-cell subpopulations and immunomodulatory effects after adding Chinese herbal medicine. METHODS: Randomized methods were used to divide the patients into the chemotherapy group and the control group. Peripheral blood was collected on the 7th day before operation, on the 1st, 7th, 14th, 21st, and 28th days after operation. The T cell subsets were determined by the monoclonal antibody APAAP method. The t test was used for statistical analysis. Results: The comparison between the two groups: CD3+, CD4+, CD8+, and CD4+/CD8+ all had significant differences after the 7th day after operation (P0.05-0.001). Conclusion: The traditional Chinese medicine can improve the cellular immunosuppressive state and clinical symptoms of the fluorouracil emulsion delivered by the regimen alone, and can significantly regulate the cellular immune system of the body.