神经营养因子 (NTF)是一类能对中枢和周围神经发挥营养作用的小分子肽类物质和蛋白质。随着科学的发展 ,NTF在面神经损伤及再生中的作用越来越受到关注。本文对 NTF的研究概况 ,面神经损伤后其运动神经元和周围神经 NTF受体和内源性 NTF的改变及外源性 NTF的作用予以综述 ,并提出目前存在的问题 Neurotrophic factor (NTF) is a class of small molecules that exert a nourishing effect on the central and peripheral nerves of peptides and proteins. With the development of science, the role of NTF in facial nerve injury and regeneration has drawn more and more attention. This review summarizes the research status of NTF, the changes of NTF receptors and NTF in motor neurons and peripheral nerves after facial nerve injury, and the effects of exogenous NTF on facial nerve after facial nerve injury, and presents the existing problems