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目的:观察还原型谷胱甘肽并用L-肉碱治疗急性病毒性心肌炎的临床效果。方法:选择急性病毒性心肌炎患者70例,随机分为两组:对照组(35例)给予黄芪注射液、维生素C等常规药物治疗;试药组(35例)在常规治疗的基础上加用还原型谷胱甘肽以及L-肉碱治疗。结果:试药组临床治愈率为69%,对照组临床治愈率46%,两组比较有统计学差异(P<0.05);试药组左室射血分数较对照组比较显著改善(P<0.05);未发现与药物相关的不良反应。结论:还原型谷胱甘肽并用L-肉碱能明显提高治疗急性病毒性心肌炎的临床疗效。
Objective: To observe the clinical effect of reduced glutathione and L-carnitine in the treatment of acute viral myocarditis. Methods: Seventy patients with acute viral myocarditis were randomly divided into two groups: the control group (35 cases) given Astragalus injection, vitamin C and other conventional drugs; the treatment group (35 cases) on the basis of routine treatment Reduced glutathione and L-carnitine treatment. Results: The clinical cure rate was 69% in the test group and 46% in the control group, with a significant difference between the two groups (P <0.05). The left ventricular ejection fraction of the test group was significantly improved compared with the control group (P < 0.05); no drug-related adverse reactions were found. Conclusion: Reduced glutathione and L-carnitine can significantly improve the clinical efficacy of treatment of acute viral myocarditis.