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近年来,胆硷能神经阻滞剂山茛菪硷(化学合成品称654—2)广泛用于临床,现将其主要用途加以介绍.一、胃、肠、胆绞痛:654—2对痉挛的胃、肠、胆道平滑肌有明显的松弛作用.经临床验证,该药对胃、肠、胆绞痛等症有解痉止痛的功效.二、慢性气管炎、支气管哮喘:654—2治疗慢性气管炎的作用,可能与解除支气管平滑肌痉挛、调节植物神经功能、改善微循环、调节人体内在因素等作用有关。中国人民解放军163医院等报道,用该药治疗308例,其有效率达77.7~95%,显效率为54.7~72.7%。治慢性气管炎以平喘和消除哮鸣音疗效较好;对肺气肿气短亦有一定疗效,约半数以上患者在3天内起效。一般用量每次为10毫克,每日3次,10天一疗程。该药超声雾化吸入,每次
In recent years, the cholinergic nerve blockers scopolamine (654-2 Chemical Synthesis said) is widely used in clinical, now its main purpose to be introduced .A stomach, intestine, biliary colic: 654-2 pairs Spasm of the stomach, intestine, bile duct smooth muscle obvious relaxation effect.Clinical validation, the drug on the stomach, intestines, biliary colic and other antispasmodic analgesic effect. Second, chronic bronchitis, bronchial asthma: 654-2 treatment The role of chronic bronchitis, bronchial smooth muscle spasm may be relieved, regulating autonomic function, improve microcirculation, regulating the body’s internal factors and so on. People’s Liberation Army 163 Hospital and other reports, the treatment of 308 cases of the drug, the effective rate of 77.7 ~ 95%, markedly effective rate was 54.7 ~ 72.7%. Chronic bronchitis to asthma and eliminate wheeze better curative effect; shortness of breath have a certain effect of emphysema, about more than half of patients in 3 days onset. The general amount of 10 mg each time, 3 times a day, 10 days a course of treatment. The medicine is sonicated by inhalation, each time