论文部分内容阅读
乙型肝炎病毒(HBV)具有高度的基因异质性,根据毒株全基因序列的异质性≥8%可分为A~H 8个基因型[1]。近年来的研究发现,HBV基因型的一个显著特征是呈一定的地理区域性分布:A型主要分布于欧洲及美国;B、C型主要分布于亚洲;D型是分布最广泛的基因型,是地中海地区和中东的优势基因
Hepatitis B virus (HBV) is highly heterogeneous and can be divided into 8 genotypes of A to H according to the heterogeneity of the whole genome sequence of the virus [1]. In recent years, the study found that a significant feature of HBV genotypes is a certain geographical distribution: A type mainly in Europe and the United States; B, C type is mainly distributed in Asia; D type is the most widely distributed genotypes, Is the dominant gene in the Mediterranean and the Middle East