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血清甲胎蛋白的来源1932年Hirszfeld等曾提示癌组织中有胚胎特异性物质存在。1963年Abelev表明实验性白鼠的肝细胞癌中存在一种癌特异性抗原,免疫学上和一种正常胎儿蛋白是相同的,作者还表明这种甲胎蛋白(AFP)是由恶性组织所再合成,并描述了许多的其他癌胚性
Sources of serum alpha-fetoprotein In 1932 Hirszfeld et al. suggested that embryo-specific substances exist in cancer tissues. In 1963, Abelev showed that there was a cancer-specific antigen in experimental hepatoma, which was immunologically identical to a normal fetal protein. The authors also showed that this alpha-fetoprotein (AFP) is re-organized by malignant tissue. Synthesis and description of many other carcinogens