Molecular recognition by gold, silver and copper nanoparticles

来源 :World Journal of Biological Chemistry | 被引量 : 0次 | 上传用户:xiaomay2
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
The intrinsic physical properties of the noble metal nanoparticles,which are highly sensitive to the nature of their local molecular environment,make such systems ideal for the detection of molecular recognition events.The current review describes the state of the art concerning molecular recognition of Noble metal nanoparticles.In the first part the preparation of such nanoparticles is discussed along with methods of capping and stabilization.A brief discussion of the three common methods of functionalization:Electrostatic adsorption;Chemisorption;Affinity-based coordination is given.In the second section a discussion of the optical and electrical properties of nanoparticles is given to aid the reader in understanding the use of such properties in molecular recognition.In the main section the various types of capping agents for molecular recognition;nucleic acid coatings,protein coatings and molecules from the family of supramolecular chemistry are described along with their numerous applications.Emphasis for the nucleic acids is on complementary oligonucleotide and aptamer recognition.For the proteins the recognition properties of antibodies form the core of the section.With respect to the supramolecular systems the cyclodextrins,calix[n]arenes,dendrimers,crown ethers and the cucurbitales are treated in depth.Finally a short section deals with the possible toxicity of the nanoparticles,a concern in public health. The intrinsic physical properties of the noble metal nanoparticles, which are highly sensitive to the nature of their local molecular environment, make such systems ideal for the detection of molecular recognition events. Current study describes the state of the art concerning molecular recognition of Noble metal nanoparticles. In the first part the preparation of such nanoparticles is discussed along with methods of capping and stabilization. A brief discussion of the three common methods of functionalization: Electrostatic adsorption; Chemisorption; Affinity-based coordination is given. in the second section a discussion of the optical and electrical properties of nanoparticles is given to aid the reader in understanding the use of such properties in molecular recognition. In the main section the various types of capping agents for molecular recognition; nucleic acid coatings, protein coatings and molecules from the family of supramolecular chemistry are described along with their numerous applications. Emphasis for the nucleic acids is on complementary oligonucleotide and aptamer recognition. For the proteins the recognition properties of antibodies form the core of the section. Due respect to the supramolecular systems the cyclodextrins, calix [n] arenes, dendrimers, crown ethers and the cucurbitales are treated in depth. Fina a short section deals with the possible toxicity of the nanoparticles, a concern in public health.
其他文献
踏进南辛安村,街道整洁,绿树成荫,农家小院错落有致,村民安居乐业,一派新农村新气象,这与往昔的南辛安村相比差距之大,让人惊诧。记者来到该村时,正值国庆节休假期间,没想到
国庆节,我和姑妈、姑父、弟弟、姐姐一起回老家。  奶奶说:“给你们烧板栗吃,好吗?”我们马上回答:“好!”  奶奶拿来一篮子板栗。板栗的果壳上长满了缝衣针般的利刺,看上去像缩成一团的刺猬。我们把板栗球一个个扔向柴灶中。奶奶叮嘱我们:“火把刺烧软后才能拿出来,但也不能把刺全烧焦了,这样板栗也会烧焦的,不好吃。”  大家都比较心急,还没几分钟,就你一言我一语地说:“应该快好了。”奶奶说还要烧一会儿,我
局限于尾状核头未破入侧脑室的脑内出血极少见,国内尚未见报道。现将我院经CT扫描证实的1例患者报道于下。 病例资料 患者,女,39岁,住院号:0435605。因突然头痛、呕吐8天于1
1986年5月17日~22日在福建漳州175医院举行了全军第三届骨科学术会议。共宣读论文386篇。现将创伤部分总结如下。创伤部分火器伤及其并发症某军区创伤骨科专业组总结了“两山
请下载后查看,本文暂不支持在线获取查看简介。 Please download to view, this article does not support online access to view profile.
在古典概型中,利用等可能性的概念,我们可以计算某一类问题的概率.不过,古典概型要求可能事件的总数必须有限.因此,历史上有不少人把这种做法推广到有无限多结果而又具有某种
本文研究了制造商态度性承诺、分销商信任与其知识转移间的关系。研究结果表明:(1)分销商的友好信任会直接促进其向制造商的知识转移,而能力信任则会加强友好信任对知识转移
党的十四大提出在我国建立社会主义市场经济体制。这是社会主义建设理论和实践的重大突破,必然引起政治、经济、文化和人们思想观念等各方面的深刻变化。新的历史任务和形势
新课标带来新教材的诞生,新课标的特点是强调学生能力和科学方法的培养,新教材如果用老教法,就会给学生带来沉重的负担.你看书本中琳琅满目的探究实验,问题讨论等等,压得学生喘不过气来,就连老师也忙不过来.无怪乎,有些教师在埋怨新教材编起来,不系统,知识体系也很凌乱,实验探究也不切合实际等等.可以说新教材中教师的教与学生的学,要比老教材的任务多得多.但就目前实验教学来看,演示和学生实验均限制在课堂这有限的
关注孩子,既是父母对孩子爱心的自然流露与表达,也是在为孩子的身心发展提供强有力的保证。父母关注孩子的时间、方式与程度,在很大程度上影响着孩子的未来发展。我们可以从