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对1986年10月～1987年4月期间住院的50例急性肝衰病人进行了前瞻性研究,以确定细菌感染发生率、发生时间、病原,以及早期细菌学诊断对临床结果的影响.50名病人中,女30名,男20名,年龄10～62岁(平均35.2岁)39名因扑热息痛中毒引起肝坏死,8名病毒性肝炎(非甲非乙5名、甲型2名、乙型1名),INH/RFP中毒2名,妊娠脂肪肝1名.病人均有Ⅱ级以上脑病(Ⅲ级7名,Ⅳ级43名).
A prospective study of 50 hospitalized patients with acute liver failure from October 1986 to April 1987 was conducted to determine the impact of bacterial infection rates, timing, pathogens, and early bacteriological diagnosis on clinical outcomes. Among the patients, 30 were women, 20 were men and 39 were aged 10-62 years (mean 35.2 years) with necrosis of the liver due to paracetamolosis. Eight patients had viral hepatitis (5 non-methylprednisolone, 2 type A and 2 type B 1), INH / RFP poisoning 2, pregnancy fatty liver 1. Patients with grade Ⅱ or more encephalopathy (Ⅲ grade 7, Ⅳ grade 43).