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目的 观察不同部位肝穿活检组织的病理学变化。方法 选择 118例乙型病毒性肝炎患者行两个穿刺点取肝组织 ,标本经常规HE染色、网状纤维及地衣红染色等特殊染色 ,普通光学显微镜观察。比较每例不同部位的病理改变。结果 两部位病理诊断一致的 78例 ,符合率占 6 6 .1%。两部位病理诊断不一致的 4 0例 ,不符合率占 33.9%。结论 病毒性肝炎时 ,肝实质的病变虽然是弥漫的 ,但炎症可以不均匀 ,同一病例不同部位的炎症程度可有明显差异。此外 ,一个部位的肝穿活检组织只能反映穿刺部位肝组织的病变情况 ,而不能代表整个肝脏炎症的轻重程度。
Objective To observe the pathological changes of liver biopsies in different sites. Methods A total of 118 cases of hepatitis B patients were selected to take liver tissue at two puncture points. Specimens were stained with HE staining, reticular fibers and lichen red staining, and observed with ordinary light microscope. Compare the pathological changes in different parts of each case. Results The pathological diagnosis of the two parts of 78 cases consistent with the rate of 66.1%. 40 cases of inconsistent pathological diagnosis of two parts, the non-coincidence rate of 33.9%. Conclusions Although the lesions of liver parenchyma are diffuse when viral hepatitis is present, the inflammation may not be uniform, and the degree of inflammation in different parts of the same case may be significantly different. In addition, a part of the liver biopsy tissue can only reflect the lesion of the liver tissue lesions, but can not represent the severity of the entire liver inflammation.