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本文报告用快速尿素酶试验检测516例有消化道不适症状的60岁以上老年患者幽门螺杆菌(HelicobacterPylori,HP)的感染情况。总感染率为37.9%。活动性慢性胃炎,胃溃疡,十二指肠球及复合溃疡HP感染率分别为86%,62.3%,63.6%和64.3%;而非动性慢性胃炎及胃癌的HP感染率分别为22.5%和24.2%。两组的HP感染率有明显差别(P<0.01)。结果提示HP感染与活动性慢性胃炎及消化性溃疡的发病有密切关系.亦可能是胃癌发生的重要始发因素之一。
This article reports the detection of Helicobacter pylori (HP) infection in 516 elderly patients over 60 years of age with gastrointestinal symptoms using the rapid urease test. The total infection rate was 37.9%. HP infection rates of active chronic gastritis, gastric ulcer, duodenal bulb and composite ulcer were 86%, 62.3%, 63.6% and 64.3%, respectively; while non-active chronic gastritis and HP infection of gastric cancer Rates were 22.5% and 24.2% respectively. HP infection rates were significantly different between the two groups (P <0.01). The results suggest that HP infection and active chronic gastritis and peptic ulcer disease are closely related. It may also be one of the important initiators of gastric cancer.