论文部分内容阅读
目的探讨脾部分切除术和部分脾栓塞术对门脉高压症患者免疫功能的影响。方法观察54例脾部分切除术和48例部分脾栓塞术治疗肝硬化脾亢术后不同时期外周血免疫球蛋白、T淋巴细胞分化抗原(CD3、CD4、CD8)的变化,以及两组患者手术前后红细胞、白细胞、血小板计数的变化。结果脾部分切除术和部分脾栓塞术后CD3、CD4、CD8无明显变化。两组患者手术后红细胞、白细胞、血小板计数均达到正常指标。结论脾脏大部切除术与部分脾栓塞术治疗PHT在对机体免疫功能的影响以及提高红细胞、白细胞、血小板记数方面大致是一致的,应该根据患者具体情况采取相应治疗方式。
Objective To investigate the effect of partial splenectomy and partial splenic embolization on immune function in patients with portal hypertension. Methods The changes of peripheral blood immunoglobulin, T lymphocyte differentiation antigen (CD3, CD4, CD8) in 54 patients with splenic cirrhosis and cirrhosis after 54 splenectomy and 48 splenic embolization were observed. Before and after the red blood cells, white blood cells, platelet count changes. Results There was no significant change of CD3, CD4, CD8 after partial splenectomy and partial splenic embolization. Two groups of patients after surgery, red blood cells, white blood cells, platelet count reached the normal indicators. Conclusions The treatment of PHT with partial splenic resection and partial splenic embolization is roughly the same in improving immune function and improving the number of erythrocytes, white blood cells and platelets. Corresponding treatment should be taken according to patients’ specific conditions.