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我国从70年代起开始将血清甲胎蛋白(AFP)应用于原发性肝癌的诊断,由于AFP具有较高的敏感性与特异性,使肝癌的诊断,治疗和预后显著提高。与此同时,上海、江苏、广西、辽宁等地在自然人群或慢性肝病患者应用血清甲胎蛋白进行广泛普查,发现一组血清甲胎蛋白低浓度持续阳性者(以下简称甲胎蛋白低持阳)与原发性肝癌的发生关系密切,为肝癌高危人群,甚至有人称其为肝癌前期病
Since the 1970s, serum AFP has been used in the diagnosis of primary liver cancer. Because of its high sensitivity and specificity, AFP has significantly improved the diagnosis, treatment and prognosis of liver cancer. At the same time, Shanghai, Jiangsu, Guangxi, Liaoning and other places in the natural population or patients with chronic liver disease serum alpha-fetoprotein for extensive screening and found that a group of serum alpha-fetoprotein sustained low positive concentration (hereinafter referred to as alpha-fetoprotein low sunshine ) Is closely related to the occurrence of primary liver cancer, which is a high risk group of liver cancer. Some people even call it liver cancer precancerous