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环孢素A(CsA)是70年代发现的具有强有力的免疫抑制剂,80年代国外开始用于器官移植抗排异反应,后期开始用于治疗难治性肾病综合征及自身免疫性疾病,国内90年代开始应用CsA抗排异反应及自身免疫性疾病。现将国内应用CsA治疗肾脏疾病的临床研究进展综述如下。
Cyclosporine A (CsA) was a powerful immunosuppressive agent found in the 1970s. In the 1980s, CsA began to be used in organ transplant rejection abroad and later was used to treat refractory nephrotic syndrome and autoimmune diseases. The domestic 90’s application of CsA anti-rejection and autoimmune diseases. Now the clinical application of CsA treatment of kidney disease in China are summarized as follows.