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目的探讨不同的保守治疗方案治疗异位妊娠的临床疗效。方法回顾性分析了2002年1月至2012年12月在我院采用不同的保守治疗方案治疗异位妊娠患者151例,总结分析两种药物组和手术保守治疗组的治疗效果。结果 A组(MTX)治愈率为82,61%;B组(MTX+RU486)治愈率为86.05%;C组(手术保守治疗)治愈率为96.77%;A组(MTX)和B组(MTX+RU486)治愈率差异无统计学意义(P>0.05);A组(MTX)与手术保守治疗C组治愈率比较差异(P<0.05);B组(MTX+RU486)与手术保守治疗C组治愈率比较也差异有统计学意义(P<0.05);C组(手术保守治疗)患者血清HCG降到正常时间明显短于药物组A组和B组(P<0.05);而A组和B组没有明显差异(P>0.05);C组血清HCG下降幅度明显大于A组和B组(P<0.05);A组和B组差异无统计学意义(P>0.05)。结论三种保守治疗早期异位妊娠均有效,手术保守治疗能缩短住院治疗时间,药物保守治疗可避免因手术给患者带来的创伤、痛苦及瘢痕、周围组织粘连和术后并发症,同时更为经济方便。治疗过程中检测血清HCG极为重要。
Objective To investigate the clinical efficacy of different conservative treatment programs for ectopic pregnancy. Methods The clinical data of 151 patients with ectopic pregnancy treated with different conservative treatment regimens in our hospital from January 2002 to December 2012 were analyzed retrospectively. The therapeutic effects of the two drug groups and conservative surgery group were analyzed. Results The cure rate of group A (MTX) was 82.61%; the cure rate of group B (MTX + RU486) was 86.05%; the cure rate of group C (conservative surgery) was 96.77%; group MTX and group B (P <0.05). There was no significant difference in the cure rates between the two groups (P> 0.05). There was no significant difference in cure rate between the two groups (P> 0.05). The cure rates of group B (MTX + RU486) (P <0.05). The serum HCG levels of patients in group C (conservative surgery) were significantly shorter than those in group A and B (P <0.05), while those in group A and B (P> 0.05). The decrease of serum HCG in group C was significantly greater than that in group A and group B (P <0.05). There was no significant difference between group A and group B (P> 0.05). CONCLUSION: All three conservative treatments are effective for early ectopic pregnancy. Conservative surgical treatment can shorten the duration of hospitalization. Conservative treatment can avoid trauma, pain and scarring caused by surgery, peripheral tissue adhesion and postoperative complications, and more For economic convenience. Detection of serum HCG during treatment is extremely important.